Anti-sperm antibody determinations
Importance in the clinical routine for the diagnosis of immunologically caused fertility disorders
Antisperm antibodies (anti-spermatozoa antibodies, sperm antibodies) in the form of autoantibodies in male and alloantibodies in female patients directed against sperm antigens may prevent fertilization of the oocyte into the female genital tract and are therefore one of the major reasons for an immunologically induced infertility. Fertility disorders of unknown etiology of male as well as female patients result to a considerable amount (up to 20%) from antisperm antibodies.
Detection of anti-sperm antibodies (anti-spermatozoa antibodies, sperm antibodies) should therefore be considered as an essential element of all infertility examinations.
For further information please send us an e-mail: info@bioserv-diagnostics.com
BIOSERV Diagnostics offers the following ready-to-use anti-sperm antibody tests:
Sperm antibody ELISA for use with serum
Sperm antibody ELISA for use with seminal plasma
Sperm antibody ELISA – Ig-classifying (Ig-typing)
Sperm antibody latex agglutination test
Sperm antibody hemagglutination test
Anti-sperm antibody ELISA for use with serum
EU registration number
DE/CA80/IVD1696
Quantitative ELISA for the detection of anti-sperm antibodies (anti-spermatozoa antibodies, sperm antibodies). This anti-sperm ELISA has been optimized for the detection of anti-sperm antibodies in human serum.
Principle of the test: Anti-sperm antibodies of the patient's sample material bind to sperm antigens immobilized on a 96-well-ELISA plate. In a second step enzyme-linked antibodies directed against human immunoglobulins are added. The antibody concentration in the patients’ serum correlates directly with the extinction values of the subsequent photometric measurements.
Sample materials: Serum.
To order the test please refer to the BIOSERV catalogue number BS-10-20.
For further information please send us an e-mail: info@bioserv-diagnostics.com
Sperm antibody ELISA for use with seminal plasma
EU registration number
DE/CA79/mv-i1809
Quantitative ELISA for the detection of anti-sperm antibodies (anti-spermatozoa antibodies, sperm antibodies). This anti-sperm ELISA has been optimized for the detection of anti-sperm antibodies in human seminal plasma.
Principle of the test: Anti-sperm antibodies of the patient's sample material bind to sperm antigens immobilized on a 96-well-ELISA plate. In a second step enzyme-linked antibodies directed against human immunoglobulins are added. The antibody concentration in the patients’ serum correlates directly with the extinction values of the subsequent photometric measurements.
Sample materials: Seminal plasma
To order the test please refer to the BIOSERV catalogue number BS-10-21.
For further information please send us an e-mail: info@bioserv-diagnostics.com
Anti-sperm antibody ELISA - Ig-classifying (Ig-typing)
EU registration number
DE/CA80/IVD1700
Quantitative ELISA for the class-specific (anti-sperm IgA, anti-sperm Ig-G) detection of anti-sperm antibodies (anti-spermatozoa antibodies, sperm antibodies).
After determination of anti-sperm antibodies (anti-spermatozoa antibodies, sperm antibodies) with the BIOSERV anti-sperm ELISA a classification of these immunoglobulins (IgG, IgA, IgM) may be carried out.
Principle of the test: Anti-sperm antibodies (anti-spermatozoa antibodies, sperm antibodies) of the patient's sample material bind to sperm antigens immobilized on a 96-well-ELISA plate. In the second step enzyme-linked antibodies directed against human immunoglobulins of the classes IgG, IgM and IgA are used. The antibody concentration in the patients’ serum correlates directly with the extinction values of the subsequent photometric measurements.
Sample materials: Serum.
To order the test please refer to the BIOSERV catalogue number BS-10-50.
For further information please send us an e-mail: info@bioserv-diagnostics.com
Anti-sperm antibody latex agglutination test
EU registration number
DE/CA80/IVD1707
By means of the sperm-antibody latex agglutination test even smallest amounts of sample material (ejaculate, serum) can be examined for the presence of sperm antibodies (anti-spermatozoa antibodies, sperm antibodies).
Principle of the test:
Only if antibodies directed against
sperm antigens are present in sample materials to be examined, latex particles
coated with this antigen will agglutinate within 1 - 2
minutes. The test is carried out on special slides delivered with the kit. All
steps are easy to follow, diagnosis is quickly achieved and the titer of the
sperm antibodies can subsequently be determined.
Sample materials: serum,
seminal plasma.
To order the test please refer to the BIOSERV catalogue number BS-10-10.
For further information please send us an e-mail: info@bioserv-diagnostics.com
Anti-sperm antibody hemagglutination test
EU registration number
DE/CA80/IVD1704
With this test sperm antibodies (anti-spermatozoa antibodies, sperm antibodies) possibly causative for fertility disorders in the serum of men and women are diagnosed and the titer is determined.
Principle of the test: The test is based upon specially pretreated and sensitized red blood cells (SRBC) coated with sperm antigen. Antibodies in the sample agglutinate with coated SRBC within 120 min.
Sample material: Serum
To order the test please refer to the BIOSERV catalogue number BS-10-30.
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For further information please send us an e-mail: info@bioserv-diagnostics.com